Disease
Vampires are the exception, capable of simply flushing out most toxins by spending a single point of Vitae. Note that vampires are rarely affected by poisons or disease, although they can become carriers. Even terminal diseases can be cured this way, though they are treated as aggravated damage for the purposes of healing them.
Elements
Undead creatures, like vampires and mummies, have nothing to fear from
hypothermia or heat stroke. Air pressure means a mild discomfort, or at
most a small amount of bashing damage. Radiation poisoning, desert
exposure, and toxic fumes are of little concern, save for vampires and the
desert sun. These beings suffer the same effects of heavy snowfall, rain,
and high winds as mortals do, but their powers give them an edge. The
undead suffer no ill effects at all from extreme environments up to level
three, and suffer level four environments as mortals do lower-level
conditions (i.e., bashing damage equal to the environment’s level once per
hour, after a number of hours equal to the character’s Stamina). Even
then, their undead bodies resist such conditions to an incredible degree,
subtracting their Supernatural Tolerance trait from the damage
sustained.