cadet branch of Takeda clan, by the Ogasawara clan who descended from Seiwa Genji, famous for Miyoshi Nagayoshi; no direct relation to the Fujiwara-descent Miyoshi clan (三吉氏).
At the beginning of the 14th century AD, Ogasawara Nagafusa settled in Shikoku. His descendant in the 8th generation settled in the district of Miyoshi (Awa province) and took the name of the place. They were great vassals of the Hosokawa clan then all powerful in Shikoku.
During the Sengoku, they controlled several provinces, including Settsu (present-day Kinki region) and Awa. Though they would fade from prominence, the Ogasawara, a clan closely related to them, would continue as a major political force throughout the Edo period.[1]
Among the retainers to the clan were Matsunaga Danjo Hisahide and his son Hisamichi from the Matsunaga clan during the Sengoku period.