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The Lamiae (singular Lamia) were a bloodline of the Cappadocian Clan, founded by Lamia (a rumored descendant and high priestess of Lillith). Members of this bloodline served the Cappadocians as dervishes and warriors until the purge orchestrated by the Giovanni, in 1444 ce

According to the Giovanni, when Lamia herself was diablerized, she passed on the curse to the Giovanni, which manifested as the Giovanni's extraordinarily painful Kiss.