The Cartels of Mexico & Central America undergo a novel privation, as they no longer benefit from the high profits of US drug prohibition - the laws are intact but enforcement has been lax so prices have dropped. Sensing a weak moment in the US with its overseas entanglements, they join forces and declare themselves of the previous CIA "leadership." This is the formation of La Sindicación ("La Sín"), which becomes a regional power with the means of a super-state.