The Museum of Science and Industry is a private, non-profit science museum located in Jackson Park, the Hyde Park neighbourhood, Chicago, Illinois. It is adjacent to Lake Michigan and The University of Chicago campus.
The museum is housed in the Palace of Fine Arts from the 1893 World's Columbian Exposition. Initially endowed by Sears, Roebuck and Company president and philanthropist Julius Rosenwald and supported by the Commercial Club of Chicago, it opened in 1933 during the Century of Progress Exposition.
Among the museum's most notable exhibits are a full-size replica coal mine, German submarine U-505 submarine captured during World War II, a United Airlines Boeing 727, the Pioneer Zephyr (the first streamlined diesel-powered passenger train in the US); the command module of the Apollo 8 spacecraft, and a 3,500-square-foot (330 m2) model railroad. Permanent or special exhibits cover manufacturing, environmental science, chemistry, physics, computers, the brain, mechanics of the human body, and agricultural science, among other subjects.