Powered is the official, legal terminology for individuals with extra-normal abilities, no matter what the origin of those abilities are. All laws and regulations referring to individuals with abilities that a normal human couldn't do use this term. In common language, the word "Powered" is used interchangeably with words like Superhero or Supervillain. There are people who do not have any extra-normal abilities who are considered "Powered" in the legal sense, these are both heroes and villains who don't have powers but can stand toe-to-toe with ones who do.