Unorganized
Upsides
Str +2, Con +2, size increase to Huge, claws and teeth as natural weapons, all unarmed attacks increase to 1d10+Str
Downsides
Int is reduced to 1, Wis is reduced to 1, inability to distinguish friend from foe, alignment change to CE, inability to use weapons, curse cannot be removed unless the sufferer is killed or the person's soul truly repents for their actions, character is taken over by the DM