The central column of the Host Tower houses the Archmage, the highest position within the Arcane Brotherhood. This is the position held for a long time by the notorious Arklem Greeth, later a Lich and generally awful being. Each of the four compass-oriented towers houses one of the Overwizards. In addition, each school of magic has a High Master that oversees that field of study's research and collected lore and artifacts.
Leaders and High Masters
| Archmage: Cashaan the Red | Necromancy |
| Overwizard of the North: Druette "the Raven" Pentecost | Transmutation |
Overwizard of the East: | Enchantment |
Overwizard of the South: | Abjuration |
Overwizard of the West: | Divination |
| Lord Renn Sadar | Conjuration |
| Moymanth Autumnsong | Illusion |
| Kaeran Altarstone | Evocation |
Cashaan the Red
- (RED) Cashaan el Farid, human male Necromancer from Calimshan.
- Archmage of the Host Tower.
- Hold-out after the fall of the Host Tower, helped remove the lingering undead after the Sundering.
- Meticulously works to control all around him, driven by his upbringing at the mercy of Genasi oppressors.
- Self-assigned envoy to Ship Baram.
Druette the Raven
- (SPECKLED BLACK) Druette Pentecost, human female Transmuter from Waterdeep.
- Overwizard of the North Tower.
- Head of a respected Waterdhavian merchant guild, rumored past ties to the Kraken Society.
- Cold, calculating with no humor and does not like wasting time, money, or talent.
- Strict advocate for asserting legitimacy and order in Luskan to bring trade and wealth to the tower.
- Monitoring the Council of Waterdeep and its interactions with the Cult of the Dragon.
- Appears a freckled auburn-haired 19 year old, but is much older.
- Assigned as envoy to Ship Taerl.
Teyva the Gray
- (GREY) Teyva "Magehand" Lillowind, half-elf human female Enchanter from Baldur's Gate.
- Overwizard of the East Tower.
- Reputation as a Rogue and "self-taught" wizard, once a member of Baldur's Gate's Guild and an ally of its leader Nine-Fingers Keene.
- Playful and immensely clever, outwits and charms even without her magics.
- Strongly backs Druette's aspirations for stimulating trade, knowing Baldur's Gate is likely the richest source of wealth as the risks and fears of piracy in Luskan's past are removed.
- Assigned as envoy to Ship Suljack.
Jendrick the Blue
- (DARK BLUE) human male Abjurer from the nearby town of Port Llast.
- Overwizard of the South Tower.
- Connected through a line of blood and line of teacher-apprentices to several past prominent leaders of the Arcane Brotherhood.
- Most consistent challenger to Cashaan as Archmage, believes himself the only one deserving the title and plays loose with the rules and has many side-projects to build his own power and influence.
- Assigned as envoy to Ship Rethnor.
Zelenn the White
- (WHITE) moon elf female Diviner from Neverwinter.
- Overwizard of the West Tower.
- Oldest (most likely) of the leaders, lived in Neverwinter long before the Spellplague and has strong ties to Dagult Neverwinter.
- Her long life makes her extremely patient and calm in her actions - starkly contrasting the urgency of the other (impatient) leaders, which leads to suggestions she is ineffective, taking too long to do things and should be replaced.
- Neverwinter's recent rebuilding and rise and the past Luskan-Neverwinter conflicts finding peace make her connections extremely valuable in making sure the Arcane Brotherhood can influence if not control its leaders.
- Her history marks her an enemy of Thay, the Zhentarim, Cult of the Dragon and the Hidden Lords of Waterdeep.
- Assigned as envoy to Ship Kurth (and somewhat secretly, a trusted ally of the Bregan D'aerthe).
Lord Renn Sadar
- (PURPLE) human male Conjurer (High Master) from Candlekeep.
- Deposed Head of noble House Sadar and banished from Candlekeep for his conniving ruthlessness in seeking power.
- Has a history of allying himself with all sorts of villains and dark powers, but is unquestionably competent and a staunch ally of Cashaan (and rival of Jendrick).
- He is always frowning and generally unpleasant to be around, makes little effort in politeness, and his school is run with intense discipline.
Moymanth Autumnsong
- (COLORS OF AUTUMN) wood elf male Illusionist (High Master) from Silverymoon.
- Conspirator with Teyva to irritate their fellow leaders, often takes the punishments for the pair.
- Extremely forgiving of people's histories and backgrounds, sees each day as a fresh page to write.
- This has led to taking chances on some students that took disastrous turns for the Arcane Brotherhood, but he has also produced some strong allies.
- Generally not trusted as reliable or devoted to the pursuit of knowledge and power, but he is so quirky and weaves his own storyline like an illusion itself, he is easily forgotten and overlooked as other matters steal away attention.
Kaeran Altarstone
- (GOLD) human male Evoker (High Master) from somewhere far away (believed in Kara-Tur).
- He has repeatedly demonstrated loyalty, courage and dedication to the Arcane Brotherhood, its protection and pursuit of knowledge and power.
- He has shown no ambition or threat to any of the others' power or positions, and treats all with respect if not kindness.
- He is truly a master of his magics and his classes are some of the most popular in the tower, with students enthusiastically pushing forward its research and knowledge.
- Because of all these benefits and lack of concern, his flat refusal to share any information of his past is accepted and everything about him prior to joining the tower remains a mystery.