In Curse Of Strahd, The Pack encountered Drusilla at the Blue Water Inn. Shakti of the Wildhunt got information on her master out of her, in exchange for the promise of apples. She eventually left with van Richten as he fled the city when Strahd von Zarovich descended, galloping all the way to Khazan's Tower.
There, she mostly stayed inside, though van Richten ventured twice on information-gathering quests. On his second, he was attacked by a Werewolf pack led by Kiril Stoyanovich. Though he barely escaped alive up the Old Svalich Road, Drusilla was torn apart by the savage monsters and eaten.